Mol Endocrinol — Furthermore, no significant activation of NR5A was observed with other estrogenic compounds, although a reproducible but modest increase in reporter activity was noted with genistein Fig 3C. Toxicol Appl Pharmacol 44— Pair your accounts. KeyMichael W.
Environ Health Perspect — A gauge steel cannula attached to polyethylene tubing was inserted to the desired depth, and the compound was injected in a controlled manner using a syringe pump Razel Scientific, St.
Distribution of serotonin receptor subtypes, and absence of striosome and matrix organization. Levels in the CxD were unchanged across both groups. However, other studies suggest that reduced serum testosterone after ATR exposure results from a marked drop in body weight and food consumption.
Alternatively, the differing 5-HT levels might result from the differential amount of activation of serotonergic neurons in specific brain nuclei, a possibility that warrants further analysis.
Another mechanism by which hormones affect neurotransmitter dynamics is by altering mRNA and protein levels of specific receptor subtypes. In zebrafish Danio rerioregulating aromatase expression is more complex because of gene duplication.
Support Center Support Center. To correct for nonlinearity, 14 C standards were used for calibration purposes. Martin P. Freitas, Cherry T.
As part of the modification, a small plastic support stick was taped securely to the bite bar. Top panels are representative photomicrographs of the site of injection arrow into the POA left but not into the VMN of the same animal right.
Polybrominated diphenyl ethers PBDEs are ubiquitous pollutants that can exert immunotoxicity, making them of interest to test effects on amphibian immune function. It is noteworthy that an increase in amygdalar serotonergic activity is thought to underlie territorial acquisition, whereas a decrease in raphe serotonergic activity accompanies behavioral sex reversal in the saddleback wrasse In situ hybridization.
Animals were then subjected to the same injection paradigm as OVX plus T animals.